Dr. Elena Salvatore even opened a practice in Mystic Falls.
Damon and Elena should be in town, and it would be nice to see them — especially Damon, since the Salvatore school bears his name and includes the Stefan Salvatore memorial library in honor of his brother.
The Vampire Diaries ended with Damon as a new human, starting a family with Elena.
Ian Somerhalder may never return to the role of Damon for Legacies, since he’s busy with his new vampire show, but it would make sense to see him again.