I suppose Whose Line Is It Anyway? fits that same mold, but she’s the only host there, so she’s integral.
Which is completely understandable, since it’s the one of her four shows that can go on the easiest without her presence, considering she wasn’t even there during the first year.
As stated during her tear-filled explanation on The Talk, Aisha Tyler simply has too many TV shows on her plate right now, along with the interesting in moving toward directing feature films, so leaving The Talk at the end of this season makes the most sense for her career.