Melinda May has been part of Agents of S.H.I.E.L.D. since it premiered in September 2013.
By this point, Phil Coulson was back in the field, and he made a passing comment to Mack about S.H.I.E.L.D.’s new director.
So now we know that Coulson isn’t in charge anymore, and while the identity of this new director hasn’t been disclosed yet, actor Clark Gregg knows which character he wants to lead S.H.I.E.L.D.: Melinda May.
At the end of the _Agents of S.H.I.E.L.D. _Season 3 finale, the show fast forwarded six months after Hive’s defeat and Lincoln Campbell’s death.