Marvel won’t tell Tom Holland who Spider-Man is fighting in next summer’s Avengers: Infinity War.
In fact, he has one fight scene in The Avengers: Infinity War where he is completely unaware of who his opponent is.
While Thanos is of course set up to be the main antagonist in The Avengers: Infinity War, his history shows that he will probably not fight many battles on his own.
And the character has already been promised even more, with both a sequel to Homecoming and an appearance in the upcoming Infinity War.