A week ago, Deadpool big bad Ed Skrein was cast as Major Ben Daimio, a canonically Japanese-American character who joined up with the B.P.R.D. after a run-in with a Bolivian jaguar-god.
The problem with this is that Ed Skrein is, obviously, not Japanese-American.
Including Skrein himself who, after some careful thought on the matter, decided to step down from the role.