While filming this scene, Jonah Hill casually dropped D.T.F. on set while ad-libbing, and thus the term D.T.F. was born.
The scene in question features Hill’s character, Seth, telling his other pal Evan about how he plans to hook up with a girl he likes.
The scheme involves first buying a shitton of alcohol for her upcoming party and then using that alcohol as leverage to hook up with her on some level.
During the conversation, he’s talking about possibly making out or fooling around with the girl at the party and then potentially working into actually dating her and getting laid before college.