The damage wasn’t always intentional, but many people might have still been alive in the Vampire Diaries universe if the brothers had never become vampires.
Instead, he was looking at the ending from an ethical standpoint, and he’s definitely not wrong that the Salvatore brothers wreaked a lot of havoc during their long lives.
Between Stefan the Ripper and Damon the human blood-drinker, they killed a lot of people and did a lot of damage to the world around them.
Ian Somerhalder shared his thoughts on the Vampire Diaries series finale at the recent Wizard World Comic Con in New Orleans, and he was careful to clarify afterward that his idea for a change didn’t mean that he hates Elena as a character or Delena as a relationship.