Both Josh Brolin and Benicio Del Toro return from the first movie but, sadly, due to his commitments on Blade Runner 2049, Denis Villeneuve, who directed the first movie, was not available to come back.
Could director Denis Villeneuve return to the director’s chair for Sicario 3?
As for Denis Villeneuve, he’s currently working on his Cleopatra movie and his big-budget Dune reboot, which he has big aspirations for.
According to producer Ed McDonnell, Villeneuve would like to come back for Sicario 3, if it happens.