Back in 2005 Tim Story became the first (save an unreleased Roger Corman project) to make a big screen Fantastic Four movie, so you can be sure he has some thoughts on what to do with the characters going forward.
The exact future of the Fantastic Four on the big screen is uncertain, but it seems quite clear that, at some point, one way or another, the first family of superhero comics is going to make their debut in the Marvel Cinematic Universe.