Michonne had saved Andrea’s life – a moment that got reversed in Gurira’s final episode – and joined up with Team Family, setting the path to a Richonne romance that never went down in the source material.
Though Michonne was first introduced on The Walking Dead at the tail end of Season 2, Danai Gurira didn’t get to share screentime with Andrew Lincoln until Season 3, and things immediately took a turn from the comics at that point.
Meanwhile, Andrea ended up getting into a baffling romance with The Governor, only to later be killed off, even though Rick and Andrea were the comic’s core coupling (beyond Maggie and Glenn, of course).