Based on the same-named series of books by Joanna Cole and Bruce Degen, the original Magic School Bus series followed Valerie Frizzle, voiced by Lily Tomlin, taking her students aboard a transforming, yellow school bus fantastical field trips, from shrinking down to venture inside of a human body, to traveling to historical time periods.
Tomlin scored the 1996 Emmy for Outstanding Performer in an Animated Program for the Ms. Frizzle role, and the series itself, which ran from 1994-1997, scored numerous Emmy nominations, among other accolades.