Superhero comics have long allegorized the plight of marginalized groups, including LGBT people, without actually representing those marginalized groups.
Seeing Deadpool get a serious same-sex love interest would mean the genre finally putting its money where its mouth is.
It’s also worth noting that Deadpool director Tim Miller was the first creator to label the character “pansexual” — and ardently so.
The only potential hurdle between a male/male romance and Deadpool 2 (aside from respectfully breaking up Wade and Vanessa) is tone.