The framework is a digital world in which anybody alive or dead can appear, and we now know of one former villain who will turn up in the not-too-distant future: Sunil Bakshi.
The agents are currently stuck inside a framework reality controlled by a rogue android, originally called A.I.D.A. and now going by Madame Hydra.
The stories of ABC’s Agents of S.H.I.E.L.D. got pretty crazy over the first few seasons, but the final third of Season 4 might deserve the prize for the craziest.