Agents of S.H.I.E.L.D. season 5 premieres midseason in 2017-2018 on ABC on Fridays, following the first season of Inhumans.
Agents of S.H.I.E.L.D. took a number of dramatic measures in its fourth season to avoid going stale, such as the addition of Ghost Rider and the alternative reality known as The Framework, and largely, these were well received.
Never a show to rest on its laurels, the S.H.I.E.L.D. season 4 finale set up a number of intriguing new mysteries to lead viewers into the fifth season.
[SPOILERS for those not caught up on Agents of S.H.I.E.L.D. ahead.]