Entertainment Weekly asked Jon Watts if the timeline literally begins with the big bang and while he couldn’t recall exactly, it sounds like it begins with some of the earliest events that would have happened within the Marvel universe.
What’s interesting is that the scroll apparently doesn’t only keep track of the MCU, but it actually covers the timeline of the entire universe.
Everything that has occurred within the MCU, whether or not we’ve seen it, or potentially, whether or not the event actually had an impact on the MCU in any way.