A Star is Born marks her first go at being a leading lady, with her strong vocal skills also pivotal to her character.
The project has been in development for quite some time, with Beyoncé (as Ally) and Clint Eastwood (as director) previously attached.
Bradley Cooper then stepped up three years ago as both director and lead.
While Lady Gaga and theatricality has always mixed well together, the singer only started showing off her acting chops as Bertha in Sin City: A Dame to Kill For and the Countess on American Horror Story: Hotel, the latter of which had her taking home a Golden Globe in 2016.