The show had already been picked as the century’s best period drama in a Radio Times poll.
Call The Midwife has been voted the best drama of the 21st century.
The poll was split into six categories, period drama, crime drama, US drama, foreign language drama, sci-fi drama and contemporary drama, with the public then asked to decide the nation’s overall favourite.
Call The Midwife executive producer Dame Pippa Harris said: “It’s an extraordinary honour to have topped this poll, and the whole Call The Midwife team are delighted.