Barb & Star Go to Vista Del Mar was helmed by Josh Greenbaum (New Girl, Becoming Bond) from a screenplay co-written by Wiig and Mumolo.
This film marked the second collaboration between Wiig and Mumolo, whom previously worked together on the award-winning comedy film Bridesmaids which starred Maya Rudolph, Wiig, Melissa McCarthy and Rose Byrne.
Jessica Elbaum’s female-focused production company Gloria Sanchez Productions produced the project together with Wiig and Mumolo alongside Will Ferrell, Adam McKay, and Margot Hand.