Co-creator Marta Kauffman has stated that the show was about a time in life when friends are family; given that the finale ended with the friends working on their own families, their priorities would be different if the show returned.
He’s not the only person from the show to debunk the possibility of a revival, although his reasons are different.
Short of Friends pulling a Will and Grace and just pretending that the original ending never happened, a revival almost certainly wouldn’t deliver what fans are looking for.
David Crane’s comments at a panel of comedy showrunners (via The Wrap) indicate that the beloved sitcom won’t return to the airwaves with new episodes at any point.