Last night’s episode of the US series – season 15 episode 15 – saw it become the longest-running prime time medical drama in the US, overtaking previous victor, ER.
The episode, titled “We Didn’t Start the Fire”, brings the show’s overall tally to 332.
The overall record is held by BBC series Casualty, which has aired in the UK since 1986.
Grey’s Anatomy, which stars Ellen Pompeo, will extend its reign thanks to an already confirmed season 16, which will begin later this year.