The novel Ready Player One is very much the story of a male nerd with an obsession with pop culture.
Trailers for Ready Player One do appear to indicate that female characters will be a bigger part of the movie, those roles that do exist seem to be expanded, but they’re still an obviously small part of the overall story.
There is clearly interest, but that interest seems to be mostly male with female moviegoers so far not all that excited.
On the plus side, there’s still time for the buzz around this one to build, so its possible things could change.