Ayesha is directly responsible for the creation of Adam Warlock (whose origins are revealed during Guardians of the Galaxy Vol. 2’s credits), so it stands to reason that she will become a key player in future adventures.
James Gunn has already made it abundantly clear that he intends to use the Ayesha character again during his next forays into the MCU, which means her status as a key player in the silver screen comic book world just became far more permanent.
Based on what we already know about the future of the Marvel Cinematic Universe, it seems increasingly likely that Elizabeth Debicki can expect even more of those pesky non-disclosure agreements on the horizon.