We know from the Harry Potter books that of Grindelwald’s biggest objectives was to get rid of the International Statute of Wizarding Secrecy, so that witches and wizards could live and practice magic out in the open.
The recent trailers for Fantastic Beasts also tease rising tension in New York among No-Majes who are professing the existence of wizards.
We know that the U.S. Ministry of Magic We’re also seeing headlines (and hearing mentions) that Gellert Grindelwald is behind a series of attacks in Europe.
If all of these factors are connected, it may be a strong indication that the first Fantastic Beasts movie is going to lay the foundation for that story to unfold even further.