The series will examine the dynamics between tribes native to the areas being explored by the trappers and the Europeans who arrive to chase pelts, so plenty of other folks will certainly be dying.
There is no word of how many episodes we can expect for Season 2, but THR notes that Jason Momoa has been confirmed as returning.
The first season is actually going to be pretty short, so the guarantee of a second season could be helpful to any who binge-watch.