I think, if given the right material, John Krasinski could a wonderful addition to the DC movies or a whole new property of his own invention.
Before Spider-Man: No Way Home director Jon Watts deservedly earned that gig, Krasinski would have also been my first choice to helm the project.
For most fans, the number one choice to play their flexible leader, Reed Richards, has been John Krasinski (along with his real-life spouse and collaborator Emily Blunt as Invisible Woman).
However, that does not mean there is no chance of him bringing his talents to the comic book movie genre one day.