The situation is much creepier this time, however, as the character in question is Michael Schofield’s (Wentworth Miller) mentally ill escaped cellmate known as Haywire (Silas Weir Mitchell), who is asked by Cuoco’s character, Sasha, to buy beer for her and her boyfriend – setting off a chain of events that results in Haywire assaulting her abusive, alcoholic father.
In 2007, months before debuting Penny on The Big Bang Theory, Kaley Cuoco starred on a pair of episodes from Season 2 of Prison Break and, in yet another common theme among many of her guest appearances, plays a teenage girl who catches the eye of one of the main characters.