Although we don’t know at this point if Infinity War will follow the same total plotline, we do know that Thanos is on a quest for the Infinity Stones.
We also know, just from comics related to the topic–and maybe some common sense–that Nebula should play a pretty interesting part in Infinity War.
In addition, in the Infinity Gauntlet storyline, she successful managed to take the Gauntlet from Thanos after he amassed the Infinity Stones and was a key part of the storyline that followed.
To find out about what we can anticipate from Avengers: Infinity War take a look at our full what we know guide.