Lea Thompson is up for the job and her previous connection to the character would bring out the cult fans of the original movie as well as people who just want to see what the heck a second Howard the Duck movie would look like.
Howard the Duck is an established character in the MCU thanks to his two Guardians of the Galaxy appearances.
We know that Phase Four of the MCU plans to be more cosmic focused, so a feature starring Howard could very well fit within Marvel’s larger plans.
Now, we just need to talk James Gunn into working on the screenplay, and we could have a winner.