Surprisingly, the film has done particularly well in China, taking $46.2 million (£37.7 million) and beating Warner Bros. The Lego Batman Movie, which took just $3.6 million (£2.9 million).
While falling short of Deadpool’s opening weekend – $132.4 million (£108 million) in the US alone – the huge box-office taking marks the biggest domestic opening of the year so far.
Over the weekend, the highly anticipated third Wolverine outing Logan reached cinemas, marking Fox’s second R-Rated superhero release following Deadpool.
Meanwhile, in second place at the US box office is Get Out, the much-hyped horror that has won rave reviews across the board.