Neal H. Moritz (Sonic the Hedgehog, Bloodshot) has also signed on to produce the project through his Original Film banner.
Ride or Die will follow the story of robbery detective Martin Banks, a consummate professional, and narcotics detective and unapologetic butt-kicker Tami Moore.
Marlon Wayans has already appeared in a number of comedy films such as Scary Movie, White Chicks, Little Man, Norbit, A Haunted House, Heat and Sextuplets.
According to The Hollywood Reporter, White Chicks star Marlon Wayans has officially set up his next film with the forthcoming buddy-cop romantic comedy titled Ride or Die, which is being likened to When Harry Met Sally but with guns.