I tend to prefer Melissa McCarthy in supporting or co-lead roles, but the box-office numbers speak for themselves: McCarthy sells tickets.
[Steve] Mallory, McCarthy and Falcone have a history of working together, most recently teaming on the Universal comedy The Boss, which grossed $78.8 million worldwide.
Melissa McCarthy in a comedy about the singularity sounds like a pretty solid premise for yuks.
According to Box Office Mojo, five of the last eight Melissa McCarthy movies have grossed more than $100 million at the domestic box office.