Deadpool actually makes fun of their absence and the current Deadpool has played no role in the X-Men films.
Ostensibly Deadpool and Deadpool 2 take place in the X-Men franchise yes, yet there has been no crossover in any significant way.
Now there are some who will undoubtedly say, “What are you talking about, they are already in the same universe?”
Wade Wilson never actually meets the core X-Men team, instead finding the X-Mansion with a population of Colossus and Negasonic Teenage Warhead and now Yukio.