The original Paddington made $268m (£203m) globally, the fourth biggest film TWC has been involved with since launching in 2005.
Paddington 2 is the biggest of seven films TWC is involved with that is scheduled for release in the coming months.
The UK producer of the Paddington films is seeking to scrap the Weinstein Company’s lucrative deal to distribute the upcoming sequel in the US, in the wake of the sexual harassment and assault allegations against its co-founder Harvey Weinstein.
It is the eighth biggest film the Weinsteins have distributed in the US, where they take their cut from the success of the Paddington films, making it a lucrative franchise the company can ill afford to lose.