The stakes were raised on several fronts: Maggie probably has metastatic breast cancer (and now only one kidney), April might be pregnant, Ethan didn’t have the most enthusiastic response to April maybe being pregnant, Dr. Charles married his dying ex-wife, and Natalie and Will were seriously injured after a vengeful criminal rammed Will’s car with his own vehicle.
The Season 4 finale of Med actually did feel like a finale, so that gives it an edge on Chicago Fire.