Judd Apatow (Freaks and Geeks, Girls) and Amy Zvi (I Love You, America) also will executive-produce Silverman’s pilot.
Silverman previously hosted I Love You, America, a late-night-style Hulu series she also created and executive-produced.
America, Sarah Silverman still loves you, and she wants to keep in touch.
The comedian will host and executive-produce a potential late-night show on HBO that will feature live interaction with viewers, the network announced Monday.