I can’t see this new version of Spider-Man rushing into another version of The Green Goblin, but like I said, this is a do-over, and the suggestion that Ned Leeds is going to be a character at least hints at the possibility that Peter’s best friend in the new story could eventually turn into his nemesis.
Could the seeds be being laid for Ned Leeds to eventually become some version of a Goblin?
However, there are alternate versions of Ned Leeds in Ultimate Marvel, and in the animated series, so there are plenty of different ways that they are able to use the character.