Variety reports that Ackles will make her Supernatural debut in the thirteenth episode of Season 13, which is forebodingly titled “Devil’s Bargain.”
She’ll catch the attention of none other than Lucifer, although Lucifer’s plans for her may be different than what we expect of him.
Danneel Ackles has been cast as a character known as “Sister Jo,” and she’ll turn up later in Season 13, presumably after the events of next week’s midseason finale have died down a little bit.
He could always just kill her… or he might have a grander purpose in mind for her.