She made a name for herself voicing the animated Harley Quinn and most recently took to the skies as the titular character in The Flight Attendant, a thrilling murder mystery on HBO Max.
Mild spoilers ahead for the season finale of The Flight Attendant.
The series returned to filming in the midst of the ongoing pandemic, which led to a funny scenario that had The Flight Attendant reusing people to film a crucial scene with Buckley.
Kaley Cuoco has been busy since wrapping up her 12-season run on The Big Bang Theory last year.