Lilly Wachowski also helmed fan-favorite Netflix series Sense8, which dealt with many themes surrounding gender and identity.
That included focusing on her transition, as well as studying art and exploring the world of stand-up comedy.
When the series was first picked up in 2015, she was still known as Andy Wachowski, and her sister Lana (formerly known as Larry) had already transitioned.
In 2016, Lilly Wachowski formally came out as a transgender woman.