It will be surprising to see Stan Lee in a movie like Spawn because most of his cameos (looking beyond the strip club scene in Tim Miller’s Deadpool) have been pretty family-friendly.
Based solely off of that description alone, it seems reasonably clear that Spawn is shaping up to give comic book icon a role that’s a far cry from his typical fare.
To build off of the fact that he intends to make his Spawn reboot a gritty, violent, and downright nasty cinematic outing, MacFarlane has described Stan Lee’s potential appearance in the movie as an “anti-cameo,” in the sense that he will not be the friendly, happy-go-lucky guy that we see in most of his on-screen appearances.