The Vampire Diaries spin-off The Originals will be ending after season 5.
This also does not mean the end for The Vampire Diaries world Plec has created; there have been talks about a possible spin-off featuring Caroline Forbes (Candice King) and her boarding school for magically inclined children, where Hope currently is, which was introduced during the season finale of The Vampire Diaries.
For now though, fans are going to have to wait and see of any news comes out of SDCC regarding the future of The Vampire Diaries world, and any further spin-offs.
The Originals will return to The CW for its fifth and final season in 2018.