Before going further, it’s worth noting that Daniel Espinosa worked with Tom Hardy on 2015’s Child 44, a Cold War-set mystery thriller that also starred Gary Oldman, Noomi Rapace and Joel Kinnaman.
The first Morbius trailer revealed that Keaton will pop up alongside in the movie, although it still hasn’t been officially confirmed if he’s reprising Adrian Toomes from Spider-Man: Homecoming.
So Espinosa simply could have been referring to his experience with Hardy on that movie, but the fact that he grouped the actor with Jared Leto and Michael Keaton is interesting.