The entire story of the first Avatar began when Jake Sully took over for his twin brother as part of the Avatar program on Pandora.
Alternatively, this could be a reference to Jake Sully starting a family, though now I’m wondering if such a thing is even possible as an Avatar.
Is he talking about the family that Jake Sully had as a human or the one he will build as a member of the Na’vi?
We thought that would be the end of it, but maybe Jake’s attempts to leave his human life behind will be more difficult if his family becomes part of the story.