As you might imagine, a nuclear weapon going off in a city is the kind of event that would easily require the work of more than one superhero to clean up, and while Ralph, Cisco and Caitlin are no slouches in the helping people department, this sounds like the kind of thing where super speed would be especially handy to get people out of the blast zone as quickly as possible.
And, it certainly sounds like Jesse and Jay will return to Central City just in time.
It’s probably a safe bet that Barry will be glad to see his friends again and get some assistance, too.
We don’t know yet who will set off a nuke in the city’s hub, but it’s either a pretty nasty villain who’s interested in doing the most damage possible, or a huge accident that someone is certain to pay for big time.