Scroll through the below gallery to see who made the cut – warning: some spoilers for classic TV shows within.
In celebration of Headey’s magnificent performance, we count down the greatest TV villains of all time, featuring characters ranging from shows such as Deadwood, EastEnders and Lost.
Game of Thrones continues on Sunday and will be available on Sky Atlantic and NOW TV in the UK.
Whether it’s a character you love to hate or one you simply hate, without them, your favourite shows just wouldn’t be the same.