Agents of S.H.I.E.L.D. season 4 premiere September 20, 2016 in its new timeslot, 10:00 PM EST on ABC.
[SPOILERS for Agents of S.H.I.E.L.D. Season 3 ahead.]
One other possibility is that the new love interest and Ghost Rider will be one and the same, since traditionally Ghost Rider exists in a human form when not using (or being used by) his powers.
Now, it’s been revealed that the season will also feature another big change for one of the series’ main characters.