Also starring in the movie is Jennifer Jason Leigh (The Hateful Eight, Anomalisa), Tessa Thompson (Thor: Ragnarok, Creed), Gina Rodriguez (Jane the Virgin, Deepwater Horizon), Tuva Novotny (Eat Pray Love, ID:A) and Oscar Isaac (Star Wars: The Last Jedi, Inside Llewyn Davis).
Just click on the player below to see what the cast has to say about being part of such an important movie for pop culture.
Annihilation is out in theaters on February 23, 2018.
Natalie Portman (Jackie, Black Swan) is Lena, a biologist and ex soldier who joins an expedition to the mysterious Area X, with the goal of discovering her husband’s fate.