And arguably the most memorable version of this was Slime Time Live!, the interstitial game show that let viewers phone in to play interactive games to try and get people pied, slimed, etc. And the dedicated host for all that messy outdoor fun (from 2000-2003) was Dave Alizer, who made it into the Guinness Book of World Records as part of the 762 people slimed in the series finale.
One thing that has always made Nickelodeon feel like a real friend to children is how it makes sponsor breaks as fun for viewers as the shows themselves.
Having to deal with screaming kids everyday had to be rough, but Aizer took it (and an assortment of other things) like a champ.