The novel focuses on the Klondike gold rush of the 1890s from the point of view of a sled dog named Buck.
The outlet notes that the project will rely heavily on the special effects studio Technoprops, purchased by Fox last year.
Ford will play John Thornton, a prospector braving the Yukon on the hunt for gold.
The big-budget live-action film is being directed by Oscar nominee Chris Sanders (The Croods, How to Train Your Dragon) from a screenplay by Oscar nominee Michael Green (Logan, American Gods).