In any case, this clip shows just how unique MacFarlane still is in the world of animation.
How many other animated series creators out there would be able to produce entirely new material on the fly, from the joke-writing to the voice-recording?
After getting that “WHO’s on first?” bit concerning the World Health Organization, I think the only thing that would have made Stewie and Brian’s podcast better, perhaps, would be an additional behind-the-scenes video that showed Seth MacFarlane recording the voices opposite himself (with even more MarFarlane’s showing up later in the video when Peter and Quagmire are heard).